2025

Damiani T, Jarmusch AK, Aron AT, Petras D, Phelan VV, Zhao HN, Bittremieux W, Acharya DD, Ahmed MMA, Bauermeister A, Bertin MJ, Boudreau PD, Borges RM, Bowen BP, Brown CJ, Chagas FO, Clevenger KD, Correia MSP, Crandall WJ, Crüsemann M, Fahy E, Fiehn O, Garg N, Gerwick WH, Gilbert JR, Globisch D, Gomes PWP, Heuckeroth S, James CA, Jarmusch SA, Kakhkhorov SA, Kang KB, Kessler N, Kersten RD, Kim H, Kirk RD, Kohlbacher O, Kontou EE, Liu K, Lizama-Chamu I, Luu GT, Luzzatto Knaan T, Mannochio-Russo H, Marty MT, Matsuzawa Y, McAvoy AC, McCall LI, Mohamed OG, Nahor O, Neuweger H, Niedermeyer THJ, Nishida K, Northen TR, Overdahl KE, Rainer J, Reher R, Rodriguez E, Sachsenberg TT, Sanchez LM, Schmid R, Stevens C, Subramaniam S, Tian Z, Tripathi A, Tsugawa H, van der Hooft JJJ, Vicini A, Walter A, Weber T, Xiong Q, Xu T, Pluskal T, Dorrestein PC, Wang M. (2025) A universal language for finding mass spectrometry data patterns. Nat Methods. doi: 10.1038/s41592-025-02660-z.

Pourmohsenin B, Wiese A, Ziemert N. (2025) AutoMLST2: a web server for phylogeny and microbial taxonomy. Nucleic Acids Res. gkaf397. doi: 10.1093/nar/gkaf397.

Sanchez-Rendon JC, Hundsdorfer L, Bastounis EE. (2025) Protocol for characterizing cell motility and extracellular signal-regulated kinase dynamics in epithelial monolayers using FRET imaging data. STAR Protoc. 6(2):103816. doi: 10.1016/j.xpro.2025.103816.

Tran SL, Lebreuilly L, Cormontagne D, Samson S, Tô TB, Stosskopf M, Dervyn R, Grießhammer A, de la Cuesta-Zuluaga J, Maier L, Naas T, Mura S, Rognan D, Nicolas J, André G, Ramarao N. (2025) An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens. Nat Commun. 16(1):3324. doi: 10.1038/s41467-025-58282-8.

Olayo-Alarcon R, Amstalden MK, Zannoni A, Bajramovic M, Sharma CM, Brochado AR, Rezaei M, Müller CL. (2025) Pre-trained molecular representations enable antimicrobial discovery. Nat Commun. 16(1):3420. doi: 10.1038/s41467-025-58804-4.

Baur ST, Schulz S, McCluskey JB, Velázquez Gómez JA, Angenent LT, Molitor B. (2025) Deletion of aldehyde: ferredoxin oxidoreductase-encoding genes in Clostridium ljungdahlii results in changes in product spectrum with various carbon sources. Bioresour Technol. 132596. doi: 10.1016/j.biortech.2025.132596.

Ye X, Shalev O, Ratzke C. (2025) Biotic resistance predictably shifts microbial invasion regimes. Nat Commun. 16(1):3952. doi: 10.1038/s41467-025-59285-1.

Clavel T, Faber F, Groussin M, Haller D, Overmann J, Pauvert C, Poyet M, Selkrig J, Stecher B, Typas A, Vehreschild MJGT, Westermann AJ, Wylensek D, Maier L. (2025) Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research. Nat Biotechnol. doi: 10.1038/s41587-025-02660-6.

Boudrioua A, Joiner JD, Grin I, Kronenberger T, Korotkov VS, Steinchen W, Kohler A, Schminke S, Schulte JC, Pietsch M, Naini A, Kalverkamp S, Hotop SK, Coyle T, Piselli C, Coles M, Rox K, Marschal M, Bange G, Flieger A, Poso A, Brönstrup M, Hartmann MD, Wagner S. (2025) Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity.  Sci Adv. 11(15):eadr5235. doi: 10.1126/sciadv.adr5235.

Chang TH, Cardona Gloria Y, Hellmann MJ, Richardo T, Greve CL, Le Roy D, Roger T, Bork F, Bugl S, Jakob J, Sonnberger J, Kasper L, Hube B, Pusch S, Gow NAR, Sørlie M, Tøndervik A, Moerschbacher BM, Weber ANR. (2025) Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing. Front Immunol. 16:1497174. doi: 10.3389/fimmu.2025.1497174.

Quinlan ZA, Nelson CE, Koester I, Petras D, Nothias LF, Comstock J, White BM, Aluwihare LI, Bailey BA, Carlson CA, Dorrestein PC, Haas AF, Wegley Kelly L. (2025) Microbial Community Metabolism of Coral Reef Exometabolomes Broadens the Chemodiversity of Labile Dissolved Organic Matter. Environ Microbiol. 27(3):e70064. doi: 10.1111/1462-2920.70064.

Krusche J, Beck C, Lehmann E, Gerlach D, Daiber E, Mayer C, Müller J, Onallah H, Würstle S, Wolz C, Peschel A. (2025) Characterization and host range prediction of Staphylococcus aureus phages through receptor-binding protein analysis. Cell Rep. 44(3):115369. doi: 10.1016/j.celrep.2025.115369.

Lebtig M, Peschel A, Kretschmer D. (2025) Role of Formyl Peptide Receptor 2 and Toll-Like Receptor 2 in Skin Barrier Function and Atopic Dermatitis. J Invest Dermatol. S0022-202X(25)00100-9. doi: 10.1016/j.jid.2025.02.002.

Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. (2025) Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun. 16(1):2760. doi: 10.1038/s41467-025-57979-0.

Wilcken S, Koutsandrea P-H, Bakker T, Kulik A, Orthwein T, Franz-Wachtel M, Harbig T, Nieselt KK, Forchhammer K, Brötz-Oesterhelt H, Macek B, Mordhorst S, Kaysser L, Gust B. (2025) The TetR-like regulator Sco4385 and Crp-like regulator Sco3571 modulate heterologous production of antibiotics in Streptomyces coelicolor M512. Appl Environ Microbiol. 2025 Apr 4:e0231524. doi: 10.1128/aem.02315-24.

Wagner B, Geibel C, Stadelmann A, Rapp J, Link H, Nussbaum E, Grenzendorfer H, Albrecht R, Hartmann M, Forchhammer K, Selim K, Hughes C, Petras D. (2025) Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding. bioRxiv 2025.04.03.647050; doi: 10.1101/2025.04.03.647050.

Li N, Deshmukh MV, Sahin F, Hafza N, Ammanath AV, Ehnert S, Nüssler A, Weber A, Jin T, Götz F. (2025) Staphylococcus aureus thermonuclease NucA is a key virulence factor in septic arthritis. Commun Biol. 2025 Apr 10;8(1):598. doi: 10.1038/s42003-025-07920-4.

Salzer A, Ingrassia S, Iyer P, Sauer L, Rapp J, Dobritz R, Müller J, Link H, Wolz C. (2025) (p)ppGpp-mediated GTP homeostasis ensures survival and antibiotic tolerance of Staphylococcus aureus. Commun Biol. 2025 Mar 28;8(1):508. doi: 10.1038/s42003-025-07910-6.

Shen L, Zhu X, Jiang H, Zhang J, Chen C, R Reinfelder J, Kappler A, Fang L, Liu T, Liu C, Wu Y, Li F. (2025) Physical Contact between Bacteria and Carbonaceous Materials: The Key Switch Triggering Activated Carbon and Biochar to Promote Microbial Iron Reduction. Environ Sci Technol. doi: 10.1021/acs.est.4c14024.

Nikeleit V, Maisch M, Straub D, Eroglu S, Lopez-Rivoldi JC, Strauss H, Ring-Hrubesh F, Byrne JM, Kappler A, Bryce C.(2025) Cryptic iron cycling influenced by organic carbon availability in a seasonally stratified lake. FEMS Microbiol Ecol.101(4):fiaf029. doi: 10.1093/femsec/fiaf029.

Becker S, Dang TT, Wei R, Kappler A. (2025) Evaluation of Thiobacillus denitrificans' sustainability in nitrate-reducing Fe(II) oxidation and the potential significance of Fe(II) as a growth-supporting reductant. FEMS Microbiol Ecol.101(4):fiaf024. doi: 10.1093/femsec/fiaf024.

Sandforth L, Raverdy V, Sandforth A, Bauvin P, Chatelain E, Verkindt H, Mingrone G, Guidone C, Verrastro O, Zhou K, Archid R, Mihaljevic A, Caiazzo R, Baud G, Marciniak C, Chetboun M, Ganslmeier M, Minelli Faiao V, Heni M, Fritsche L, Moller A, Kantartzis K, Peter A, Lehmann R, Wagner R, Prystupa K, Fritsche A, Stefan N, Preissl H, Birkenfeld AL, Jumpertz von Schwartzenberg R, Pattou F. (2025) Subphenotype-Dependent Benefits of Bariatric Surgery for Individuals at Risk for Type 2 Diabetes. Diabetes Care. dc250160. doi: 10.2337/dc25-0160.

Gomez-Escribano JP, Zimmermann A, Xia SN, Döppner M, Moschny J, Hughes CC, Mast Y. (2025) Application of a replicative targetable vector system for difficult-to-manipulate streptomycetes. Appl Microbiol Biotechnol. 109(1):89. doi: 10.1007/s00253-025-13477-3.

Li N, Deshmukh MV, Sahin F, Hafza N, Ammanath AV, Ehnert S, Nüssler A, Weber ANR, Jin T, Götz F. (2025) Staphylococcus aureus thermonuclease NucA is a key virulence factor in septic arthritis. Commun Biol. 8(1):598. doi: 10.1038/s42003-025-07920-4.

Orthwein T, Alford JT, Becker NS, Fink P, Forchhammer K. (2025) Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC. mBio. e0337824. doi: 10.1128/mbio.03378-24.

Deschner F, Mostert D, Daniel JM, Voltz A, Schneider DC, Khangholi N, Bartel J, Pessanha de Carvalho L, Brauer M, Gorelik TE, Kleeberg C, Risch T, Haeckl FPJ, Herraiz Benítez L, Andreas A, Kany AM, Jézéquel G, Hofer W, Müsken M, Held J, Bischoff M, Seemann R, Brötz-Oesterhelt H, Schneider T, Sieber S, Müller R, Herrmann J. (2025) Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets. Cell Chem Biol. 32(4):586-602.e15. doi: 10.1016/j.chembiol.2025.03.005.

Bhattarai K, Majer T, Haussmann M, Schollmeyer D, Kramer M, Oni FE, Höfte M, Voget R, Gütschow M, Ruetalo N, Schindler M, Straetener J, Wannenwetsch T, Brötz-Oesterhelt H, Karongo R, Masberg B, Lämmerhofer M, Hennessy RC, Muletz-Wolz CR, Gross H. (2025) Salamandamide Lipodipeptides Are Biosynthetic Intermediate Shunt Products of the Nonamodular Nonribosomal Peptide Assembly Lines of the Viscosin Family. J Nat Prod. doi: 10.1021/acs.jnatprod.5c00084.

Reetz L, Schulze L, Kronenberger T, Selim KA, Schaefle T, Dema T, Zipperer A, Mößner J, Poso A, Grond S, Peschel A, Krismer B. The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism. mBio. (2025) doi: 10.1128/mbio.03571-24.

Gericke N, Beqaj D, Kronenberger T, Kulik A, Gavriilidou A, Franz-Wachtel M, Schoppenmeier U, Harbig T, Rapp J, Grin I, Ziemert N, Link H, Nieselt K, Macek B, Wohlleben W, Stegmann E, Wagner S. Unveiling the substrate specificity of the ABC transporter Tba and its role in glycopeptide biosynthesis. iScience. (2025) doi: 10.1016/j.isci.2025.112135

Temovska M, Hegner R, Ortiz-Ardila AE, Usack JG, Angenent LT. (2025) Lactate production from lactose-rich wastewater: A comparative study on reactor configurations to maximize conversion rates and efficiencies. Water Res. 278:123365. doi: 10.1016/j.watres.2025.123365.

Medeiros W, Kralova S, Oliveira V, Ziemert N, Sehnal L. Antarctic bacterial natural products: from genomic insights to drug discovery. Nat Prod Rep. doi: 10.1039/d4np00045e.

Fink P, Menzel C, Kwon JH, Forchhammer K. (2025) A novel recombinant PHB production platform in filamentous cyanobacteria avoiding nitrogen starvation while preserving cell viability. Microb Cell Fact. 24(1):43. doi: 10.1186/s12934-025-02650-y.

Sandforth L, Kullmann S, Sandforth A, Fritsche A, Jumpertz-von Schwartzenberg R, Stefan N, Birkenfeld AL. (2025) Prediabetes remission to reduce the global burden of type 2 diabetes. Cell Press. doi: 10.1016/j.tem.2025.01.004.

Stephens BM, Stincone P, Petras D, English CJ, Opalk K, Giovannoni S, Carlson CA. (2025) Oxidation state of bioavailable dissolved organic matter influences bacterioplankton respiration and growth efficiency. Commun Biol. 8(1):145. doi: 10.1038/s42003-025-07574-2.

Alexander KL, Naman CB, Iwasaki A, Mangoni A, Leao T, Reher R, Petras D, Kim H, Ternon E, Caro-Diaz EJE, Glukhov E, Mitrevska JA, Avalon NE, Duggan BM, Gerwick L, Gerwick WH. (2025) Fatuamide A, a Hybrid PKS/NRPS Metallophore from a Leptolyngbya sp. Marine Cyanobacterium Collected in American Samoa. J Nat Prod.  doi: 10.1021/acs.jnatprod.4c01051.

Xu X, Mansor M, Li G, Chiu TH, Haderlein SB, Kappler A, Joshi P. (2025) Size-Dependent Reduction Kinetics of Iron Oxides in Single and Mixed Mineral Systems. Environ Sci Technol. 59(5):2519-2530. doi: 10.1021/acs.est.4c08032.

Krysenko S, Emani CS, Bäuerle M, Oswald M, Kulik A, Meyners C, Hillemann D, Merker M, Prosser G, Wohlers I, Hausch F, Brötz-Oesterhelt H, Mitulski A, Reiling N, Wohlleben W. (2025) GlnA3_Mt is able to glutamylate spermine but it is not essential for the detoxification of spermine in Mycobacterium tuberculosis. J Bacteriol. e0043924. doi: 10.1128/jb.00439-24.