Publikationen

Wilcken S, Koutsandrea P-H, Bakker T, Kulik A, Orthwein T, Franz-Wachtel M, Harbig T, Nieselt KK, Forchhammer K, Brötz-Oesterhelt H, Macek B, Mordhorst S, Kaysser L, Gust B. (2025) The TetR-like regulator Sco4385 and Crp-like regulator Sco3571 modulate heterologous production of antibiotics in Streptomyces coelicolor M512. Appl Environ Microbiol. 2025 Apr 4:e0231524. doi: 10.1128/aem.02315-24.

Wagner B, Geibel C, Stadelmann A, Rapp J, Link H, Nussbaum E, Grenzendorfer H, Albrecht R, Hartmann M, Forchhammer K, Selim K, Hughes C, Petras D. (2025) Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding. bioRxiv 2025.04.03.647050; doi: 10.1101/2025.04.03.647050.

Li N, Deshmukh MV, Sahin F, Hafza N, Ammanath AV, Ehnert S, Nüssler A, Weber A, Jin T, Götz F. (2025) Staphylococcus aureus thermonuclease NucA is a key virulence factor in septic arthritis. Commun Biol. 2025 Apr 10;8(1):598. doi: 10.1038/s42003-025-07920-4.

Salzer A, Ingrassia S, Iyer P, Sauer L, Rapp J, Dobritz R, Müller J, Link H, Wolz C. (2025) (p)ppGpp-mediated GTP homeostasis ensures survival and antibiotic tolerance of Staphylococcus aureus. Commun Biol. 2025 Mar 28;8(1):508. doi: 10.1038/s42003-025-07910-6.

Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. (2025) Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun. 2025 Mar 20;16(1):2760. doi: 10.1038/s41467-025-57979-0.

Salzer A, Ingrassia S, Iyer P, Sauer L, Rapp J, Dobritz R, Müller J, Link H, Wolz C. (2025) (p)ppGpp-mediated GTP homeostasis ensures survival and antibiotic tolerance of Staphylococcus aureus. Commun Biol. 8(1):508. doi: 10.1038/s42003-025-07910-6.

Shen L, Zhu X, Jiang H, Zhang J, Chen C, R Reinfelder J, Kappler A, Fang L, Liu T, Liu C, Wu Y, Li F. (2025) Physical Contact between Bacteria and Carbonaceous Materials: The Key Switch Triggering Activated Carbon and Biochar to Promote Microbial Iron Reduction. Environ Sci Technol. doi: 10.1021/acs.est.4c14024.

Nikeleit V, Maisch M, Straub D, Eroglu S, Lopez-Rivoldi JC, Strauss H, Ring-Hrubesh F, Byrne JM, Kappler A, Bryce C.(2025) Cryptic iron cycling influenced by organic carbon availability in a seasonally stratified lake. FEMS Microbiol Ecol.101(4):fiaf029. doi: 10.1093/femsec/fiaf029.

Becker S, Dang TT, Wei R, Kappler A. (2025) Evaluation of Thiobacillus denitrificans' sustainability in nitrate-reducing Fe(II) oxidation and the potential significance of Fe(II) as a growth-supporting reductant. FEMS Microbiol Ecol.101(4):fiaf024. doi: 10.1093/femsec/fiaf024.

Sandforth L, Raverdy V, Sandforth A, Bauvin P, Chatelain E, Verkindt H, Mingrone G, Guidone C, Verrastro O, Zhou K, Archid R, Mihaljevic A, Caiazzo R, Baud G, Marciniak C, Chetboun M, Ganslmeier M, Minelli Faiao V, Heni M, Fritsche L, Moller A, Kantartzis K, Peter A, Lehmann R, Wagner R, Prystupa K, Fritsche A, Stefan N, Preissl H, Birkenfeld AL, Jumpertz von Schwartzenberg R, Pattou F. (2025) Subphenotype-Dependent Benefits of Bariatric Surgery for Individuals at Risk for Type 2 Diabetes. Diabetes Care. dc250160. doi: 10.2337/dc25-0160.

Gomez-Escribano JP, Zimmermann A, Xia SN, Döppner M, Moschny J, Hughes CC, Mast Y. (2025) Application of a replicative targetable vector system for difficult-to-manipulate streptomycetes. Appl Microbiol Biotechnol. 109(1):89. doi: 10.1007/s00253-025-13477-3.

Li N, Deshmukh MV, Sahin F, Hafza N, Ammanath AV, Ehnert S, Nüssler A, Weber ANR, Jin T, Götz F. (2025) Staphylococcus aureus thermonuclease NucA is a key virulence factor in septic arthritis. Commun Biol. 8(1):598. doi: 10.1038/s42003-025-07920-4.

Orthwein T, Alford JT, Becker NS, Fink P, Forchhammer K. (2025) Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC. mBio. e0337824. doi: 10.1128/mbio.03378-24.

Wilcken S, Koutsandrea P-H, Bakker T, Kulik A, Orthwein T, Franz-Wachtel M, Harbig T, Nieselt KK, Forchhammer K, Brötz-Oesterhelt H, Macek B, Mordhorst S, Kaysser L, Gust B. (2025) The TetR-like regulator Sco4385 and Crp-like regulator Sco3571 modulate heterologous production of antibiotics in Streptomyces coelicolor M512. Appl Environ Microbiol. e0231524. doi: 10.1128/aem.02315-24.

Deschner F, Mostert D, Daniel JM, Voltz A, Schneider DC, Khangholi N, Bartel J, Pessanha de Carvalho L, Brauer M, Gorelik TE, Kleeberg C, Risch T, Haeckl FPJ, Herraiz Benítez L, Andreas A, Kany AM, Jézéquel G, Hofer W, Müsken M, Held J, Bischoff M, Seemann R, Brötz-Oesterhelt H, Schneider T, Sieber S, Müller R, Herrmann J. (2025) Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets. Cell Chem Biol. 32(4):586-602.e15. doi: 10.1016/j.chembiol.2025.03.005.

Bhattarai K, Majer T, Haussmann M, Schollmeyer D, Kramer M, Oni FE, Höfte M, Voget R, Gütschow M, Ruetalo N, Schindler M, Straetener J, Wannenwetsch T, Brötz-Oesterhelt H, Karongo R, Masberg B, Lämmerhofer M, Hennessy RC, Muletz-Wolz CR, Gross H. (2025) Salamandamide Lipodipeptides Are Biosynthetic Intermediate Shunt Products of the Nonamodular Nonribosomal Peptide Assembly Lines of the Viscosin Family. J Nat Prod. doi: 10.1021/acs.jnatprod.5c00084.

Reetz L, Schulze L, Kronenberger T, Selim KA, Schaefle T, Dema T, Zipperer A, Mößner J, Poso A, Grond S, Peschel A, Krismer B. The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism. mBio. (2025) doi: 10.1128/mbio.03571-24.

Gericke N, Beqaj D, Kronenberger T, Kulik A, Gavriilidou A, Franz-Wachtel M, Schoppenmeier U, Harbig T, Rapp J, Grin I, Ziemert N, Link H, Nieselt K, Macek B, Wohlleben W, Stegmann E, Wagner S. Unveiling the substrate specificity of the ABC transporter Tba and its role in glycopeptide biosynthesis. iScience. (2025) doi: 10.1016/j.isci.2025.112135

Temovska M, Hegner R, Ortiz-Ardila AE, Usack JG, Angenent LT. (2025) Lactate production from lactose-rich wastewater: A comparative study on reactor configurations to maximize conversion rates and efficiencies. Water Res. 278:123365. doi: 10.1016/j.watres.2025.123365.

Medeiros W, Kralova S, Oliveira V, Ziemert N, Sehnal L. Antarctic bacterial natural products: from genomic insights to drug discovery. Nat Prod Rep. doi: 10.1039/d4np00045e.

Fink P, Menzel C, Kwon JH, Forchhammer K. (2025) A novel recombinant PHB production platform in filamentous cyanobacteria avoiding nitrogen starvation while preserving cell viability. Microb Cell Fact. 24(1):43. doi: 10.1186/s12934-025-02650-y.

Sandforth L, Kullmann S, Sandforth A, Fritsche A, Jumpertz-von Schwartzenberg R, Stefan N, Birkenfeld AL. (2025) Prediabetes remission to reduce the global burden of type 2 diabetes. Cell Press. doi: 10.1016/j.tem.2025.01.004.

Stephens BM, Stincone P, Petras D, English CJ, Opalk K, Giovannoni S, Carlson CA. (2025) Oxidation state of bioavailable dissolved organic matter influences bacterioplankton respiration and growth efficiency. Commun Biol. 8(1):145. doi: 10.1038/s42003-025-07574-2.

Alexander KL, Naman CB, Iwasaki A, Mangoni A, Leao T, Reher R, Petras D, Kim H, Ternon E, Caro-Diaz EJE, Glukhov E, Mitrevska JA, Avalon NE, Duggan BM, Gerwick L, Gerwick WH. (2025) Fatuamide A, a Hybrid PKS/NRPS Metallophore from a Leptolyngbya sp. Marine Cyanobacterium Collected in American Samoa. J Nat Prod.  doi: 10.1021/acs.jnatprod.4c01051.

Xu X, Mansor M, Li G, Chiu TH, Haderlein SB, Kappler A, Joshi P. (2025) Size-Dependent Reduction Kinetics of Iron Oxides in Single and Mixed Mineral Systems. Environ Sci Technol. 59(5):2519-2530. doi: 10.1021/acs.est.4c08032.

Krysenko S, Emani CS, Bäuerle M, Oswald M, Kulik A, Meyners C, Hillemann D, Merker M, Prosser G, Wohlers I, Hausch F, Brötz-Oesterhelt H, Mitulski A, Reiling N, Wohlleben W. (2025) GlnA3_Mt is able to glutamylate spermine but it is not essential for the detoxification of spermine in Mycobacterium tuberculosis. J Bacteriol. e0043924. doi: 10.1128/jb.00439-24.