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Research Area C

Research Area C

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C: Bacterial Communities and Host

Which general principles are used by bacterial microbiome members and host cells to communicate and interfere with each other?

Antimicrobial host factors are critical for shaping the composition of the microbiome and individual differences in the expression of such factors contribute to microbiome dysfunction and diseases. Scientists in Research Area C will join forces to identify in human microbiomes host-produced bioactive molecules and metal-ions scavengers that restrict the growth of microorganisms.

They will then elucidate the effects of these compounds on bacterial fitness in host-specific habitats and on the dynamics of microbial communities in in vitro and in vivo microbiome model systems. The impact of specific Microbial-Associated Molecular Patterns (MAMPs) and MAMP variants on the production of antimicrobial molecules and inflammatory mediators will be further investigated in gnotobiotic transgenic mice. The long term goal of Research Area C is to unravel principles of communication between microbiomes and hosts on a systemic level.

Portrait Effie Bastounis

Effie Bastounis, PhD

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

effie.bastounis

de
Website

Portrait Franz Baumdicker

Dr. Franz Baumdicker

University of Tübingen
Department of Computer Science

franz.baumdicker

de
Website

Portrait Andreas Dräger

Jun.-Prof. Dr. Andreas Dräger

University of Tübingen
Institute for Biomedical Informatics
Computational Systems Biology

andreas.draeger

de
Website

Portrait Simon Heilbronner

Dr. Simon Heilbronner

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Infection Biology

simon.heilbronner

de
Website

Portrait Arnaud Kengmo-Tchoupa

Dr. Arnaud Kengmo-Tchoupa

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Infection Biology

arnaud.kengmo-tchoupa

mnf.uni-tuebingen.

de
Website

Portrait Ruth Ley

Prof. Ruth Ley, PhD

Deputy Spokesperson

Max Planck Institute for Biology
Managing Director
Department of Microbiome Science

ruth.ley

de
Website

Portrait Lisa Maier

Prof. Dr. Lisa Maier

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

l.maier

de
Website

Portrait Silke Peters

Prof. Dr. med. Silke Peter

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

silke.peter

med.uni-tuebingen.

de
Website

Portrait Hans-Georg Rammensee

Prof. Dr. Hans-Georg Rammensee

University of Tübingen
Institute of Cell Biology
Immunology

Website

Portrait Christoph Ratzke

Dr. Christoph Ratzke, PhD

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Systems Biology of Microbial Communities

christoph.ratzke

cmfi.uni-tuebingen.

de
Website

Portrait Alexander Weber

Prof. Dr. Alexander Weber

University of Tübingen
Interfaculty Institute for Cell Biology
Department of Immunology

alexander.weber

de
Website

Portrait Detlef Weigel

Prof. Dr. Detlef Weigel

Max Planck Institute for Biology
Molecular Biology

detlef.weigel

de
Website

Research Area A — Bacterial Molecules and Cells

Research Area B — Bacterial Cells and Communities

Research Area C — Bacterial Communities and Host

Research Area D — Towards Integrative Therapy Concepts