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Research Areas

The four research areas (A, B, C, D) work closely together to understand microbiome-host interactions. The research program maps increasingly complex interactions ranging from the molecular level (A) to the community level (B) to the microbiome-host level (C). Results from these areas are incorporated into translational integrative therapeutic approaches (D). In all four sections, the research is strongly interdisciplinary. It illuminates processes from different scientific perspectives and encourages original and synergistic collaborative research approaches.

Central questions:


Which bacterial molecules govern the specific interactions of bacterial cells with other microorganisms and host cells? (A)

Which complex interaction networks shape mutualism or antagonism along with strain evolution and adaptation in bacterial communities? (B)

Which general principles are used by bacterial microbiome members and host cells to communicate and interfere with each other? (C)

How can discoveries from the other areas be harnessed for innovative microbiome-based diagnostic, preventive, and therapeutic strategies? (D)