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Research Area A

A: Bacterial Molecules and Cells

Central question

Which bacterial molecules govern the specific interactions of bacterial cells with other microorganisms and host cells?

Aim

Bacterial fitness and microbial interactions are shaped by multiple factors, including the ability to secrete antimicrobial compounds and to colonize specific niches. Scientists in Research Area A will join forces to identify and isolate from the human microbiome new bacterial strains that produce antimicrobials. The mode of action of these molecules will then be dissected and their ecological role clarified.

In parallel, using a combination of computational, genetic, cellular and biochemical approaches, gene clusters potentially involved in glycopolymer biosynthesis will be identified and their involvement in bacterial adhesion in cooperation with adhesins further characterized in culture systems as well as animal models. The long term goal of Research Area A is to identify microbial effectors that can be targeted or exploited for therapeutic interventions.

Principal Investigators

Portrait Effie Bastounis © Leon Kokkoliadis
Effie Bastounis, PhD

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

effie.bastounis@uni-tuebingen.de
Website

Portrait Erwin Bohn
PD Dr. Erwin Bohn

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

erwin.bohn@med.uni-tuebingen.de
Website

Portait Heike Brötz-Oesterhelt © University of Tübingen/Friedhelm Albrecht
Prof. Dr. Heike Brötz-Oesterhelt

Deputy Spokesperson

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Department of Microbial Bioactive Compounds

heike.broetz-oesterhelt@uni-tuebingen.de
Website

Portrait Stephanie Grond © University of Tübingen / Jörg Jäger
Prof. Dr. Stephanie Grond

University of Tübingen
Institute of Organic Chemistry

stephanie.grond@uni-tuebingen.de
Website

Portrait Simon Heilbronner [Translate to Englisch:] © Universität Tübingen / Friedhelm Albrecht
Dr. Simon Heilbronner

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Infection Biology

simon.heilbronner@uni-tuebingen.de
Website

Chambers Hughes CMFI PI University of Tübingen © University of Tübingen / Friedhelm Albrecht
Chambers Hughes, PhD

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Microbial Bioactive Compounds

chambers.hughes@uni-tuebingen.de
Website

Portrait Bernhard Krismer © Jörg Jäger/University of Tübingen
Dr. Bernhard Krismer

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Infection Biology

b.krismer@uni-tuebingen.de
Website

Portrait Hannes Link © Max Planck Institute Marburg
Prof. Dr. Hannes Link

Board Member, Coordinator Research Area A

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Bacterial Metabolomics

hannes.link@cmfi.uni-tuebingen.de
Website

Portrait Andrei Lupas
Prof. Dr. Andrei Lupas

Max Planck Institute for Biology
Proteinevolution

andrei.lupas@tuebingen.mpg.de
Website

Portrait Bastian Molitor © Jörg Jäger, University of Tübingen.
Dr. Bastian Molitor

University of Tübingen
Center for Applied Geoscience
Environmental Biotechnology

bastian.molitor@uni-tuebingen.de
Website

[Translate to Englisch:] [Translate to Englisch:]
Prof. Dr. Thorsten Nürnberger

University of Tübingen
ZMBP
Plant Biochemistry

nuernberger@uni-tuebingen.de
Website

Portrait Daniel Petras © Leon Kokkoliadis
Dr. Daniel Petras

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Functional Metabolomics

Website

Portrait Christoph Ratzke © Jörg Jäger/University of Tübingen
Dr. Christoph Ratzke, PhD

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Systems Biology of Microbial Communities

christoph.ratzke@cmfi.uni-tuebingen.de
Website

Portrait Khaled Selim © Khaled Selim
Dr. Khaled Selim

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine

khaled.selim@uni-tuebingen.de
Website

Portrait Thilo Stehle © UKT
Prof. Dr. Thilo Stehle

University of Tübingen
Interfaculty Institute of Biochemistry
Structural Biology

thilo.stehle@uni-tuebingen.de
Website

Portrait Samuel Wagner © UKT
Prof. Samuel Wagner, PhD

Board Member, Director Graduate School IGIM

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine Tübingen
Cellular and Molecular Microbiology

samuel.wagner@med.uni-tuebingen.de
Website

Portrait Wolfgang Wohlleben
Prof. Dr. em. Wolfgang Wohlleben

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine
Microbiology/Biotechnology

wolfgang.wohlleben@biotech.uni-tuebingen.de
Website

Portrait Nadine Ziemert © UKT
Prof. Dr. Nadine Ziemert

Board Member, Equal Opportunities Officer

University of Tübingen
Interfaculty Institute of Microbiology and Infection Medicine Tübingen
Translational Genome Mining for Natural Products

nadine.ziemert@uni-tuebingen.de
Website