skip to main content

Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI)


Gut microbes and humans on a joint evolutionary journey
15.09.2022Gut microbes and humans on a joint evolutionary journey Press Release
Khaled Selim receives Nikon PostDoc Award
15.09.2022Khaled Selim receives Nikon PostDoc Award CMFI News
Humans evolved with their microbiomes
15.09.2022Humans evolved with their microbiomes In the Media


I‘m a Scientist – Infektionen
26.09.2022 – 07.10.2022I‘m a Scientist – InfektionenHeike Brötz-Oesterhelt | Online More
Microbiology and Infection Biology Day
07.10.2022Microbiology and Infection Biology Day 08:00 05:00 | Symposium More
International Conference on Gram-Positive Pathogens
09.10.2022 – 12.10.2022International Conference on Gram-Positive PathogensAndreas Peschel | Conference More

About the CMFI

The surfaces of the human body host colonies of microorganisms, known as microbiomes. Along with bacteria which have a positive effect on human health, microbiomes contain potentially life-threatening pathogens. In the past, broad-spectrum antibiotics have often been used to tackle them. Nowadays it is known that this not only promotes resistance to antibiotics – in many cases it also damages the microbiome as a whole. 


CMFI researchers aim to develop new strategies to control microbial mechanisms and fight infections.

The Cluster of Excellence CMFI brings together researchers from different disciplines such as infection biology, immunology, bioinformatics, pharmaceutical biology, antibiotics research, molecular and medical microbiology, biotechnology, environmental biology, systems biology, chemistry, and medical history and ethics. Their common goal is to elucidate the mechanisms of interaction between beneficial and harmful bacteria and the host in order to develop novel targeted therapeutic and anti-infective treatments.

The CMFI is one of more than 50 Clusters of Excellence funded by German federal and state governments as part of the Excellence Initiative to sustainably strengthen Germany as a center of science, improve its international competitiveness and make cutting-edge research at German universities visible. In addition to the University of Tübingen, the Max Planck Institute for Biology and the University Hospital Tübingen are involved in the CMFI.

More about the Research