"Paleomycin: Wiederbelebung eines Urantibiotikums" CMFI Podcast Episode 2
Episode 2: "Paleomycin: Wiederbelebung eines Urantibiotikums"
In the second episode of the podcast "Inside CMFI: Potenziale der Mikrobiomforschung”, we embark on a treasure hunt for a million-year-old primal antibiotic. Such unknown antibiotic agents are urgently needed because antibiotic resistance is increasing rapidly worldwide!
The majority of our antibiotics today are produced by bacteria. However, there are still many untapped treasures hidden in the genes of bacteria that could help us in the race against the increasingly rapid development of antibiotic resistance.
Nadine Ziemert and Evi Stegmann from the Cluster of Excellence CMFI and the Interfaculty Institute of Microbiology and Infection Medicine (IMIT) at the University of Tübingen take us on a journey through time and report on the ressurection of a primal antibiotic in the laboratory.
Using bioinformatic methods, they first trace back the evolution, determine the structure of the antibiotic substance and where its components can be found. In the laboratory, they then actually manage to produce and reassemble these components.
The primal antibiotic paleomycin has been ressurected and the treasure has been unearthed!
In the podcast “Inside CMFI”, we dive into the groundbreaking research of the CMFI at the University of Tübingen. Our experts share their knowledge about the world of microbes and talk about the discoveries in microbiome research.
Antibiotic resistance is one of the biggest problems of our time. The development of resistance is overtaking us and we are in danger of falling back into a post-antibiotic era.
How can we fight bacteria that have become resistant to antibiotics? And what new antibiotic agents are needed for this?
Researchers from the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) are addressing these questions. In the podcast “Inside CMFI”, the CMFI experts talk about the exciting aspects of their research and how we might win the fight against upcoming antimicrobial resistance.
For all those who are passionate about science: This podcast offers exciting insights into current research findings and shows what we can learn from nature in the fight against antibiotic resistance in order to develop novel therapeutic approaches.
Concept: Malte Hennig and Leon Kokkoliadis
Moderation: Malte Hennig
A podcast of the Cluster of Excellence CMFI. Funded by the German Research Foundation (DFG).
The podcast can be found on all common portals and is also available without a player directly on the podcast website https://insidecmfi.podbean.com/.
Spotify https://open.spotify.com/show/28niz6ptTRKnVEerdkgU2b?si=6a6e68a6a14f48ab
Apple Podcasts https://podcasts.apple.com/us/podcast/inside-cmfi-potenziale-der-mikrobiomforschung/id1789840599
Amazon Music https://music.amazon.com/podcasts/75bac652-2982-4f1f-90f3-c351b28bd59d/inside-cmfi-potenziale-der-mikrobiomforschung
YouTube https://www.youtube.com/playlist?list=PLB1dUBp9S4pF63frZcn6n1ftQu8rtlNki
Related Articles
