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Technician (Translational Microbiome Research)

Cluster of Excellence CMFI | now

The Lab of Translational Microbiome Research (Head: C. Stein-Thoeringer), part of the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI), at the University of Tübingen studies the cross-talk between gut microbes, pathogens, the immune milieu and environmental factors in cancer development, therapy and infections. It is located in the new M3 (Mikrobiom-Metabolom-Malignom) – Institute at the University of Tübingen. The lab’s science mission is to understand how individual bacteria, microbial consortia or microbial perturbations through diets or antibiotics interplay with inflammatory responses and metabolic disturbances to drive tumor development, infections and cancer therapies.

We are using cutting-edge wet-lab techniques combined with bioinformatic tools to sequence and to analyse the microbiome from different sites of the gastrointestinal tract applying culture-omics and high-resolution metagenome sequencing techniques. This approach is combined with multi-omics characterisation of the host’s immune system or the metabolome, and we utilize gnotobiotic model systems to infer causality in microbe-host interactions. In translational clinical approaches, we are performing clinical studies to study patient microbiomes, associations with disease and environmental factors and carry out microbiome-based interventions for the benefit of patients.

 

For a project on the role of the gut microbiome funded by the Deutsche Krebshilfe, we are looking for a Technician (f/m/d), part-time for 2 years, and offer a salary according to TV-L E9 (50%).

 

Your tasks

After a phase of introduction and teaching, you can expect varied and independent work in microbiome, immune and infection research in the following areas of responsibility:

  • You will supervise in vitro cell cultures and support in vitro microbiological experiments.
  • You will support the laboratory internal laboratory animal management and assist in in vivo mouse experiments.
  • Other tasks include performing routine laboratory methods such as RNA and DNA extraction, PCR, realtime PCR, ELISA or Western blots.
  • Documentation of your work procedures according to good scientific practice is an important part of your task.
  • Supervision of general and administrative laboratory activities.

 

Your profile

  • You have successfully completed training as a chemical/biological laboratory technician or comparable with additional function-related training or further training.
  • Previous experience in animal and microbiological research (e.g., FELASA B certificated) is an advantage.
  • You are familiar with common computer applications and documentation according to good scientific practice and you have good written and oral English skills.
  • Your working style is characterized by a sense of responsibility, self-organization and high-degree of motivation and initiative.
  • You enjoy working in an interdisciplinary team.

 

How to apply:

Applications or questions about the position should be sent to Christoph Stein-Thoeringer (christoph.stein-thoeringer@med.uni-tuebingen.de).

Please send your application as a single PDF file that includes: a cover/motivation letter; your CV/biosketch; and university transcripts.

 

The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regard to gender, race, color, national origin, sexual orientation, religion, disability, or age.

The review of applications will begin in August 2022 and will continue until the position is filled.